A common requirement for desktop applications is to handle system-wide hotkeys, in order to intercept keyboard shortcuts even when they don’t have focus. Unfortunately, there is no built-in feature in the .NET framework to do it. Of course, this is not a new issue, and there are quite a few open-source libraries that address it (e.g. VirtualInput). Most of them rely on a global system hook, which allow them to intercept all keystrokes, even the ones you’re not interested in.